The symptoms and signs of iron deficiency are partially explained by the presence of anemia. They include pallor, fatigue, poor exercise tolerance, and decreased work performance. Iron, TIBC, Copper, Zinc, Albumin binding capacity of Cobalt, Nickel, Chromium, Manganese, Cholesterol, antioxidant activity of SOD, Catalase and Lipid peroxidation were estimated in two groups. One group containing 40 individuals of age between 40 to 60 years, which served as control and in another group 40 anemic cases of the same age group were considered. The concentration of Hemoglobin significantly decreased (7.77g/dl) in Iron deficiency Anemia. When compared to normal subject (14.55µg/dl). The concentration of Iron was decreased in the anemic cases was about 54.9 µg/dl compared to control which about 163ug/dl and the total iron binding capacity (TIBC) was found to be increased. The TIBC of 40 anemic cases is 210 µg/dl compared to the normal case of about 182 µg/dl. The concentration of copper is increased slightly (173.2µg/dl) when compared to the normal subjects (155.2µg/dl). Zinc concentration has slightly decreased (52.09 µg/dl). The activity of SOD (5858.51 units/g Hb) and catalase (3609.79 units/g Hb) are increased significantly when compared to the control (4736.4 units/g Hb and 4604.64 units/g Hb). Lipid peroxidation concentration was slightly decreased when compared to the normal subject. So we observed that, in anemic subjects, a decline in the level of serum iron and zinc is associated with decreased in the level of lipid peroxidation and increased activity of SOD has been observed.
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